Dr. Bruce Pollock
Research Focus
Dr. Pollock's long-term goal is to teach and conduct research in geriatric clinical psychopharmacology. His work includes: 1) clinical studies examining neurochemical selectivity, pharmacokinetics, and neurophysiological-therapeutic effects of conventional or newly derived/modified agents for the treatment of depression and the behavioral disturbances of dementia, and 2) examination of age-related changes in drug metabolism and pharmacodynamics toward optimizing treatment with antidepressants and antipsychotics. Particular attention is given to effects on cognition, balance, psychomotor and cardiovascular function. The overarching objective of this research is improved therapeutics.Publications
Education
1987 PhD, PharmacologySchool of Medicine University of Pittsburgh, PA, USA;
1979 M.D., Medicine
Faculty of Medicine University of Toronto, Ontario, Canada;
1975 BSc, Biological Sciences
University of Toronto, Ontario, Canada;
Academic Appointments
2001-2001 ChiefAcademic Division of Geriatrics and Neuropsychiatry Department of Psychiatry University of Pittsburgh School of Medicine, Pittsburgh, PA, USA;
2000-2000 Professor of Pharmaceutical Sciences (Secondary Appointment)
2000-2000 Director
Clinical Therapeutics Research Program Department of Psychiatry University of Pittsburgh School of Medicine, Pittsburgh, PA, USA;
1997-1997 Professor of Psychiatry and Pharmacology
University of Pittsburgh School of Medicine, Pittsburgh, PA, USA;
1997-1997 Professor
School of Nursing (Secondary Appointment), Pittsburgh, PA, USA;
1991-1996 Associate Professor
Departments of Psychiatry and Pharmacology University of Pittsburgh School of Medicine , Pittsburgh, PA, USA;
1994-1996 Associate Professor
Health and Community Systems University of Pittsburgh School of Nursing (Secondary Appointment) , Pittsburgh, PA, USA;
1987-1995 Associate Director
Western Psychiatric Institute and Clinic Clinical Pharmacology Program and Clinical Psychopharmacology Core MHCRC for Affective Disorders , Pittsburgh, PA;
1991-1995 Consultant
Department of Veterans Affairs Highland Drive, Pittsburgh, PA;
1993-1993 Graduate Training Faculty
Center for Neuroscience University of Pittsburgh School of Medicine , Pittsburgh, PA, USA;
1993-1993 Conferral of Tenure
University of Pittsburgh School of Medicine , Pittsburgh, PA, USA;
1992-1992 Graduate Faculty
University of Pittsburgh School of Medicine, Pittsburgh, PA, USA;
1989-1990 Assistant Professor
Department of Pharmacology University of Pittsburgh School of Medicine , Pittsburgh, PA, USA;
1984-1990 Assistant Professor
Department of Psychiatry University of Pittsburgh School of Medicine , Pittsburgh, PA, USA;
1984-1988 Attending Staff
Mood Disorders Module Western Psychiatric Institute and Clinic , Pittsburgh, PA ;
1985-1988 Co-Director
Tourette's Syndrome Clinic ,
1983-1984 Post-Doctoral Fellow
Western Psychiatric Institute and Clinic , Pittsburgh, PA, USA;
1982-1983 Chief Resident
Clarke Institute of Psychiatry, Dept of Psychiatry , Toronto, ON, Canada;
1982-1982 Chief Resident
Clarke Institute of Psychiatry, Ambulatory Service, Toronto, ON, Canada;
1980-1981 PGY 2 Resident
Clarke Institute of Psychiatry, Primary Care Unit , Toronto, ON, Canada ;
1981-1981 PGY 3 Resident
Hincks Treatment Center for Children, Child Psychiatry , Toronto, ON, Canada ;
1979-1980 Intern
Toronto General Hospital , Toronto, ON, Canada ;
2001-2006 Associate Member
University of Pittsburgh Center for Pharmacogenetics, Pisstburgh, PA, USA;
2005-2006 Sandra A. Rotman Chair in Neuropsychiatry Professor & Head Division of Geriatric Psychiatry Senior Scientist
Centre for Addiction and Mental Health University of Toronto Faculty of Medicine, Toronto, ON, Canada;
1983-2006 Attending Staff
Clarke Institute of Psychiatry Emergency Department and Queen Street Hospital Psychogeriatric Unit, Toronto, ON;
1988-2006 Medical Staff
Department of Psychiatry, Presbyterian University Hospital Division of Geriatrics and Neuropsychiatry , Pittsburgh, PA;
1995-2006 Director
Geriatric Psychopharmacology Program,
1997-2006 Associate Director
Mental Health Clinical Research Center for Late Life Mood Disorders , Pittsburgh, PA;
Research Projects
2005-2010 Efficacy of Adjunct Sleep Interventions for PTSDInvestigators: A. Germain; B.G. Pollock (Consultant; Laboratory Support)
Sponsors: Department of Defense, $24,801 USD
2005-2010 Advanced Center for Interventions and Services Research for Late-Life Mood Disorders
Investigators: C. Reynolds B.G. Pollock;
Sponsors: National Institute of Mental Health, $2,962,260 USD
2005-2009 Maintenance Therapies in Late-Life Depression –III
Investigators: B.G. Pollock;
Sponsors: National Institute of Mental Health, $1, 988, 394 USD
2004-2009 Neuroscience-Guided Remediation of Cognitive Deficits in Schizophrenia
Investigators: S. Vinogradov; B.G. Pollock
Sponsors: National Institute of Mental Health, $36,000 USD
2003-2008 Advanced Research Institute in Geriatric Psychiatry
Investigators: M. Bruce; B.G. Pollock (Core Faculty/Mentor)
Sponsors: National Institute of Mental Health,
2003-2008 Predicting Alcoholic Treatment Response to a SSRI
Investigators: R. Anthenelli; B.G. Pollock
Sponsors: National Institute on Alcohol Abuse and Alcoholism, $55,140 USD
2003-2008 Serotonin Modulation in Geriatric Depression
Investigators: G. Smith; B.G. Pollock
Sponsors: National Institute of Mental Health, $152,560 USD
2003-2008 Depression: The Search for Treatment-Relevant Phenotypes
Investigators: E. Frank; B.G. Pollock
Sponsors: National Institute of Mental Health, $686,895 USD
2004-2007 Development of an Anticholinergic Burden Risk Assessment Tool
Investigators: B.G. Pollock (Co-Principal Investigator);
Sponsors: Janssen Pharmaceutica Inc., $204,700 USD
2003-2007 Commonwealth Center of Excellence for Bipolar Disorder
Investigators: D.J. Kupfer; B.G. Pollock
Sponsors: Commonwealth of Pennsylvania,
2002-2007 Clinical Research Training in Late-Life Mood Disorder
Investigators: C.F. Reynolds; B.G. Pollock
Sponsors: National Institute of Mental Health,
2002-2007 Medication Adherence in Older Psychotic People
Investigators: J. Lacro; B.G. Pollock
Sponsors: National Institute of Mental Health, $39,000 USD
2002-2007 Geropsychopharmacology: Enhancing Benefit, Reducing Risk
Investigators: B.G. Pollock;
Sponsors: National Institute of Mental Health, $544,390 USD
2002-2006 Anticholinergic Drugs, Cognitive Deficits & Normal Aging
Investigators: R.D. Nebes; B.G. Pollock
Sponsors: National Institute on Aging, $700,000 USD
2000-2006 Continuation Pharmacotherapy for Agitation of Dementia
Investigators: B.G. Pollock;
Sponsors: National Institute of Mental Health, $1,163,305 USD
2001-2005 Atypical Antipsychotics: Determinants of Concentration
Investigators: B.G. Pollock;
Sponsors: National Institute of Mental Health, $800,000 USD
2000-2005 IRC for the Study of Late Life Mood Disorders.
Investigators: B.G. Pollock; C.F. Reynolds
Sponsors: National Institute of Mental Health, $5,432,131 USD
2000-2005 Treatment of Resistant Depression in Adolescents
Investigators: D. Brent; B.G. Pollock (Laboratory Director)
Sponsors: National Institute of Mental Health, $15,974 USD(Lab component)
2000-2005 MHIRC for Mood and Anxiety Disorders-Treatment Indications and Optimization Core
Investigators: David J. Kupfer; B.G. Pollock
Sponsors: National Institute of Mental Health, $1,331,245 USD
2001-2004 St. John’s Wort and CYP3A metabolism in men & women
Investigators: R. Frye; B.G. Pollock
Sponsors: National Institute of Mental Health, $700,000 USD
Professional Affiliations
1981-present Canadian Psychiatric Association1984-present American Medical Association
1984-present American Psychiatric Association
1986-present American College of Clinical Pharmacology
1987-present American Federation for Clinical Research
1988-present American Geriatrics Society
1988-present American Society for Clinical Pharmacology and Therapeutics
1989-present Society of Biological Psychiatry
1991-present Canadian Academy of Geriatric Psychiatry
1992-present Pennsylvania/West Virginia Geriatrics Society
1992-present American Association for Geriatric Psychiatry
1992-present International Assoc of Therapeutic Drug Monitoring and Clinical Toxicology
2001-present American College of Neuropsychopharmacology
2001-present International College of Geriatric Psychoneuropharmacology
Reviewership : Consulting
1988-1989 Editorial Consultant, Williams & Wilkins Publishers, Baltimore, MD1989-1989 The Ontario Mental Health Foundation, Toronto
1993-present - Editorial Consultant to Drug Evaluation Program of Adis International for Drugs and Aging, CNS Drugs and Clinical Drug Investigation
1995-1996 Alzheimer Disease Study Units Steering Committee
1995-2000 Reviewer for Am Assoc Geriatric Psychiatry, Young Investigator Awards
1996-present - Reviewer for Am Assoc Geriatric Psychiatry, Annual Meeting Submissions
1995-present - Editorial Consultant, Women’s Health Advocate, San Diego, CA
1995-present - SmithKline Beecham National Advisory Panel
1997-present - Forest Laboratories National Advisory Panel
1997-present - National Institute of Mental Health, Mental Disorders of the Aging Research Branch, Ad hoc reviewer on MERIT application.
1997-1998 Advisor to American Psychiatric Association Handbook of Psychiatric Measures
1997-1998 Member, Committee on Pharmacokinetics and Drug Interactions in the Elderly. Divisions of Neuroscience and Behavioral Health and Health Policy, Institute of Medicine, National Academy of Sciences.
1998-present - Editorial Consultant to Patient Care, Med Economics Press, Montvale, NJ
1998-present - American Federation for Aging Res, Merck/AFAR Research Scholarship Program
1998-present - Medical Research Council of Canada, External Referee
1998-present - Editorial Consultant, American Geriatrics Society
1999-present - Pennsylvania Drug Use Review Board
1999-present - Advisory Committee, Sierra-Pacific MIRECC, Department of Veterans Affairs
1999-present - Scientific Advisory Board, Janus Pharmaceuticals
1999-present - Editorial Consultant, Clinical Psychiatry News
1999-present - Advisory Board, Pharmacia & Upjohn
2000-present - Geriatric Advisory Board, Organon
2000-present - National Institute of Mental Health, Special Emphasis Panel ZMH1 BRB-P 03 A
2000-present - U.S. Pharmacopeia Gerontology Expert Committee
2004-present - Food and Drug Administration, Psychopharmacologic Drug Advisory Committee
2005-present - Wellcome Trust (UK)
2005-present - Extramural Advisory Board of the National Institute on Alcohol Abuse and Alcoholism
Reviewership : Committee
1990-1991 Acting Medical Director, Diagnostic and Evaluation Center; School of Medicine, University of Pittsburgh1989-1992 Member, Institutional Review Board - Biomedical; School of Medicine, University of Pittsburgh
1988-1992 Member: Pharmacy and Therapeutics Committee, Formulary Subcommittee, Patient Medication Information Task Force; School of Medicine, University of Pittsburgh
1985-present - Reviewer for Research Committee; School of Medicine, University of Pittsburgh
1982-1983 Member, Utilization, Emergency, and Resident Education Committees; Clarke Institute of Psychiatry, University of Toronto
1982-1983 Member, Medical Advisory Committee; Clarke Institute of Psychiatry, University of Toronto
1982-1983 Executive of the Research Committee; Department of Psychiatry, University of Toronto
1981-1982 Member, Academic Lectures Subcommittee; Department of Psychiatry, University of Toronto
1980-1983 Psychiatric Residents Association of Toronto Council; Department of Psychiatry, University of Toronto
1980-1983 Member, Research Committee; Department of Psychiatry, University of Toronto
1980-1983 Member, Postgraduate Education Committee; Department of Psychiatry, University of Toronto
1980-1981 Organizing Committee, International Conference on the Future of Undergraduate Psychiatric Education; Faculty of Medicine, University of Toronto
1979-1980 Decanal Search Committee, Faculty of Medicine; Faculty of Medicine, University of Toronto
1978-1979 Chairman, Laurie Chute Award Committee; Faculty of Medicine, University of Toronto
1977-1979 Representative, University of Toronto Medical Society; Faculty of Medicine, University of Toronto
1977-1979 Council of the Faculty of Medicine, Science Policy Committee; Faculty of Medicine, University of Toronto
1991-1992 Member, Research Pharmacy Oversight Committee; School of Medicine, University of Pittsburgh
1992-1994 Alternate Member, Biomedical IRB; School of Medicine, University of Pittsburgh
1991-1993 Interviewer of Medical School Applicants; School of Medicine, University of Pittsburgh
1991-1993 Membership Committee, Pennsylvania/West Virginia Geriatrics Society
1991-1995 Member, Highland Drive VA Medical Center, Research and Development Committee; School of Medicine, University of Pittsburgh
1992-present - Member, WPIC Research Committee; School of Medicine, University of Pittsburgh
1992-present - Mentor, Program for Minority Research Training in Psychiatry
1992-1993 Allegheny County Medical Society, Bioethics Advisory Committee
1992-1995 Invited by American College of Neuropsychopharmacology to assist in prep. of the 1st written examination for the Department of Defense Psychotherapeutic Drug Training Program for Clinical Psychology
1993-present - Member, WPIC Clinical Trials Subcommittee; School of Medicine, University of Pittsburgh
1993-present - Member, Residency Recruitment Committee; School of Medicine, University of Pittsburgh
1993-1995 Member, Dept of Psychiatry, Research Strategic Planning Committee, Chairman, Psychopharmacology Research Subcommittee; School of Medicine, University of Pittsburgh
1993-1996 Elected departmental representative to the University Planning and Budgeting Committee; School of Medicine, University of Pittsburgh
1994-present - Academic Promotions Committee, Chairman, Subcommittee on Non-Tenure Stream Contract Renewals (1995-96); School of Medicine, University of Pittsburgh
1994-1995 Member, Steering Committee for UPMC Pharmacy; University of Pittsburgh Medical Center
1995-1995 Member, Pharmacy Director Search Committee; University of Pittsburgh Medical Center
1995-1995 Member, Search Committee for Puig-Antich Chair in Child Psychiatry; School of Medicine, University of Pittsburgh
1995-present - Member, Pharmacy and Therapeutics Committee; School of Medicine, University of Pittsburgh
1995-present - Member, Executive Committee of the Mental Health Clinical Research Center for the Study of Late-Life Mood Disorders; School of Medicine, University of Pittsburgh
1995-1997 Member, Competitive Medical Research Fund Review Committee; University of Pittsburgh Medical Center
1996-present - Research Committee, American Association for Geriatric Psychiatry
1996-1997 Member, Grants Process/IRB Advisory Group; School of Medicine, University of Pittsburgh
1996-1998 Member, General Clinical Research Center Advisory Committee; University of Pittsburgh Medical Center
1997-1997 Ad Hoc Sub-Committee on Treatment Algorithms, for Clinical Pathways Project; School of Medicine, University of Pittsburgh
1997-present - Chair, Departmental Quality Assurance Committee for Human Research Subjects; School of Medicine, University of Pittsburgh
1997-present - Member, Departmental Committee on Pharmaceutical Research; School of Medicine, University of Pittsburgh
1997-present - New Technology and Expert Consultant Panel, Community Care Behavioral Health
1997-present - Planning Committee for Geriatric Psychiatric Alliance Depression/Comorbidity Educational Program
1997-1998 National Academy of Sciences, Institute of Medicine, Committee on Pharmacokinetics and Drug Interactions in the Elderly
1997-1999 Program Committee for Annual Meetings, American Association for Geriatric Psychiatry
1998-present - Chair, Program Committee, 1999 Annual Meeting, American Association for Geriatric Psychiatry
1999-present - Member, Clinical Neuroscience Research Center Scientific Advisory Committee; School of Medicine, University of Pittsburgh
1999-present - Member, UPMC Health Plan Pharmacy and Therapeutics Committee; University of Pittsburgh Medical Center
1999-present - Member, Executive Committee, UPMC Stroke Institute; University of Pittsburgh Medical Center
1999-present - Member, Selection Committee for Editor-in-Chief of the American Journal of Geriatric Psychiatry
2000-present - Member, Department of Psychiatry Academic Council; School of Medicine, University of Pittsburgh
2000-present - Member, UPMC/BEST Psychotropics Subcommittee; University of Pittsburgh Medical Center
2000-present - Member, Functional Imaging Research Program, Scientific Advisory Committee; University of Pittsburgh Medical Center
2000-present - Member, University of Pittsburgh Institutional Data and Safety Monitoring Board (IDSMB); University of Pittsburgh Medical Center
2000-present - Alzheimer’s Association, committee for the J. L. Foster Lecture Series
2000-2002 Alzheimer's Association, Work Group on interventions for Alzheimer’s Disease
2000-2003 Elected to the Board of the American Association for Geriatric Psychiatry
2000-2005 U.S. Pharmacopeia Gerontology Expert Committee
2001-present - Academic Promotions Committee; School of Medicine, University of Pittsburgh
2001-present - WPIC Research Day Committee; School of Medicine, University of Pittsburgh
2001-present - International College of Geriatric Psychoneuropharmacology, Ethics Committee
2001-2002 Mayview State Hospital Collaborative Committee
2002-2002 Center for Healthy Aging, Medical Advisory Medical Advisory Board
2002-present - International College of Geriatric Psychoneuropharmacology, Co-Chair, Awards Committee
2002-2005 American Federation for Aging Research, Merck/AFAR Junior Investigator in Geriatric Clinical Pharmacology Review Committee
2004-present - Member, Scientific Advisory Board, Center for Integrative Medicine; University of Pittsburgh Medical Center
2004-2005 Secretary/Treasurer-elect, American Association for Geriatric Psychiatry
2004-2005 Planning Committee, 8th International Meeting, Clinical Pharmacology in Psychiatry
2005-2005 Departmental Senior Advisory Committee; Department of Psychiatry, University of Toronto
2005-2005 Departmental Programme Heads Committee; Department of Psychiatry, University of Toronto
2005-present - Clinical Research Infrastructure Working Group; Faculty of Medicine, University of Toronto
2005-2006 Secretary/Treasurer, American Association for Geriatric Psychiatry
2006-2006 Departmental Search Committee for Head of Neuroscience Program; Department of Psychiatry, University of Toronto
2006-2006 Departmental Centennial Event Steering Committee; Department of Psychiatry, University of Toronto
2006-present - Departmental Promotions Committee; Department of Psychiatry, University of Toronto
Reviewership : Editorial Boards
1994 Treating the Blues (Newsletter for Primary Care Physicians), Guest Editor1996 Journal of Geriatric Psychiatry and Neurology
1998 The Consultant Pharmacist
1998-2000 Issues in Depression: Index & Reviews, (Lippincott Williams& Wilkins)
2001 Geriatrics At Your Fingertips, 4-8th editions (Am Geriatrics Society)
2001-2004 The American Journal of Geriatric Psychiatry
2003 The American Journal of Geriatric Pharmacotherapy
2003 Mental Fitness
2005 Aging Health
2005 Canadian Journal of Psychiatry
2005 Current Psychiatry
1984 American Journal of Psychiatry, Washington, DC
1988 Archives of General Psychiatry, Chicago, IL
1989 Journal of Clinical Psychiatry, Memphis, TN
1989 Journal of Neuropsychiatry and Clinical Neurosciences, Washington, DC
1989 Journal of Affective Disorders, Iowa City, IA
1990 Review Board, Hospital Formulary, Cleveland, OH
1991 Journal of Clinical Psychopharmacology, Boston, MA
1992 International Journal of Geriatric Psychiatry, New York, NY
1994 CNS Drugs, Auckland, New Zealand
1994 American Journal of Geriatric Psychiatry, Washington, DC
1994 Journal of Psychiatric Research, Elsevier Science, Ireland
1995 Annals of Neurology, San Francisco
1997 Clinical Drug Investigation, Auckland, NZ
1998 Psychopharmacology, Berlin,Heidelberg, Germany
1998 Canadian Journal of Clinical Pharmacology
1998 Journal of Psychiatry & Neuroscience,Ottawa, Canada
2000 Depression and Anxiety, New York, NY
2000 Pharmacotherapy, Carlisle.
Awards
2006 The Best Doctors in America, 3rd – 10th Editions2005 Who’s Who in America, 53rd - 60th, Editions
2005 Guide to America’s Top Psychiatrists, Consumer Research Council of America
2004 Who’s Who in Medicine and Health Care, 1st – 6th Editions
2003 Distinguished Fellow, American Psychiatric Association
2003 Distinguished Scientist Award, American Association for Geriatric Psychiatry
2002 Independent Scientist Award, National Institute of Mental Health
1997 Academic Award in Geriatric Mental Health, National Institute of Mental Health
1991 Merck Fellow in Geriatric Clinical Pharmacology, American Federation for Aging Research
1986 Centennial Fellow, Medical Research Council of Canada
1983 Laughlin Fellow, American College of Psychiatrists
1979 Pfizer Pharmaceutics Research Award for Best Resident Paper, Department of Psychiatry, University of Toronto
1978 Medical Alumni-Medical Society Prose Contest Prize, Univ of Toronto
1976 Summer Scholarship, Department of Surgery, University of Toronto
1975 Dr. H.C. Parson's Scholarship, Trinity College, University of Toronto
1972 Ontario Scholar, Province of Ontario
1972 General Proficiency Prize and Bowes Prize in English
Curriculum Vitae Download
Curriculum VitaeContact
The Rotman Research InstituteBaycrest
3560 Bathurst Street, 838
Toronto, Ontario,
Canada M6A 2E1
Phone: (416) 785-2500 x2908
Fax: (416) 785-2862
Email: bpollock
rotman-baycrest.on.ca