Back to PLS HelpPLS analysis on structural images
Posted on 07/04/13 11:02:40
Number of posts: 2
Hi
Is it possible to run PLS analysis (e.g., mean center PLS) on structural images (e..g, FLAIR images)? If so, any particular steps that need to be taken? Thanks.
Ming-Ching
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Posted on 07/04/13 11:07:10
Number of posts: 229
Hi Ming-ching
no.. that should not be done.
In the same way that the intensity values in a T1-weighted image are "meaningless" from an analysis perspective - FLAIR signal intensities are also "meaningless". When we segment T1-w images, we convert the signal intensities into GM probability (etc), which then makes it possible to calclate statistics at the voxel level..
your T1/T2 maps are calculated relaxation times, so they are also suitable for voxel-based analysis.
nancy
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