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test data information
weijianing
Posted on 05/18/09 18:13:14
Number of posts: 2
weijianing posts:

Hello, I am a new user of PLS software. I just want to play with the test data, specifically fMRI data, which is download from this website. Is there any information or readme file for this data, i.e. what are the stimuli, and further descriptions of this experiment? Thank you very much.

BTW: I read the paper "Spatiotemporal analysis of event-related fMRI data using partial least squares" published in 2004. But the experimental setup described there doesn't seem to match the test data.

Jianing

Replies:

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jshen
Posted on 05/18/09 19:54:24
Number of posts: 291
jshen replies:

As far as I know, some of the test data were generated manually just for test purpose. The activation map in the brain were not obtained by stimuli from any experiment. I do not have many information about those test data, since they are just served to demonstrate the procedures that I described in the User's Guide.




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rmcintosh
Posted on 05/19/09 07:49:52
Number of posts: 394
rmcintosh replies:

The test data are from a simulation that is described in:  Della-Maggiore et al, Neuroimage,17, 19-28 (2002).  The empirical data used for the 2004 paper are not part of the test data set.  It would be too large to store on the FTP server, so we opted for the smaller simulated data.



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weijianing
Posted on 05/20/09 10:29:22
Number of posts: 2
weijianing replies:

Thank you very much for your reply. Is there anyway to know where are those truly active pixels (since this is simulated data, we should have ground truth)?


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jshen
Posted on 05/20/09 12:29:23
Number of posts: 291
jshen replies:

Active voxels can be defined as those having salient Brain LV values, including both positive values and negative values.

Here's a simple example from our Testdata:
  1. Using dataset_001 and onsets.txt to create s1_fMRIsession.mat/s1_fMRIdatamat.mat for subject1; Using dataset_002 and onsets.txt to create subject2; Do same thing to create subject3, subject4, and subject5;
  2. Put all five subjects into one group; Run Mean-Centering PLS analysis with 500 permutation tests and 81 bootstrap tests;
  3. You can find active voxels from the result file by yourself, here are some of the voxels: [41 45 2] on Lag2, [24 20 5] on Lag1, etc. I don't want to enumerate all of them.
In addition, "Testdata.zip" here are just served to demonstrate the procedures of running our PLS programs. Please focus on your own clinical or your own simulate data, and using the above definition to justify whether a voxel is active or not.

By the way, you can also adjust the positive/negative threshold if you think it is necessary. This will of cause change the activation map.




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